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Post by heatherp on Nov 14, 2014 23:36:09 GMT -5
Hi all, So Wyatt has been doing very well, diagnosed approx 8 weeks ago, 18 months old now. No more awful smell to breath, urine smells more normal, all other symptoms gone. One thing that remains is his blood sugar sits in the 70s-90s, which I think is low for his age. But all other symtpoms gone, and a happy kid to boot. Has developmental delays in general with a significant delay with regression in speech. So he got the flu shot yesterday (which may or may not have any bearing, and shouldn't I believe from reading the package inserts and researching) and since then his sweat smells very odd. Sweet but like urine. Only where he sweats...feet, back of neck, legs (footie pajamas), etc. anyone ever have this? The only other difference is he has been consuming a lot of lactose free milk in the past two days....otherwise no new foods, and the milk isn't new but rather a food he doesn't normally tolerate well so we dont normally give it (he spotted it in the fridge so I figured we'd do another trial of it). Any ideas of how I might figure out a cause to the odd smell? The smell is too pungent to be normal....something is clearly not as it should be.
Thank you!
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christopher
New Member
28y/o, suspect having FBPase deficiency. From scandinavia.
Posts: 33
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Post by christopher on Jan 27, 2016 16:41:31 GMT -5
As a grown up, I have experienced sweat smelling like urine while working out. It smells like ammonia or some would describe it as very "fishy". I donĀ“t know what caused it, but I speculate that it was caused by me ingesting a proteinshake before working out (running tough intervals) and having a version of HFI called FBPase deficiency.
The causal chain I speculate to be as follows: normally excess ingested protein would be converted by the liver into glucose through gluconeogenesis. As FBPase is the rate limiting enzyme in that process, the protein could not be removed through that pathway. As some of the aminoacids are quite toxic I believe the body chooses to excrete them as fast as possible in any way it can. Through the sweat would be one of those possible ways of excretion.
Have you noticed if the sweat that smells also feels acidic? If I remember correctly it caused a burning sensation for me, unlike what sweat normally does, also unlike the very salty kind of sweat.
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Post by stefaniebillette on Feb 15, 2016 10:46:58 GMT -5
Hi all, So Wyatt has been doing very well, diagnosed approx 8 weeks ago, 18 months old now. No more awful smell to breath, urine smells more normal, all other symptoms gone. One thing that remains is his blood sugar sits in the 70s-90s, which I think is low for his age. But all other symtpoms gone, and a happy kid to boot. Has developmental delays in general with a significant delay with regression in speech. So he got the flu shot yesterday (which may or may not have any bearing, and shouldn't I believe from reading the package inserts and researching) and since then his sweat smells very odd. Sweet but like urine. Only where he sweats...feet, back of neck, legs (footie pajamas), etc. anyone ever have this? The only other difference is he has been consuming a lot of lactose free milk in the past two days....otherwise no new foods, and the milk isn't new but rather a food he doesn't normally tolerate well so we dont normally give it (he spotted it in the fridge so I figured we'd do another trial of it). Any ideas of how I might figure out a cause to the odd smell? The smell is too pungent to be normal....something is clearly not as it should be. Thank you! Flu shot contains sorbitol. We've skipped all live vaccines for this reason.
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